Is there any chance that silicone lube left in my anus/rectum for a few days might make me sick? I’m a lesbian who likes every experience a little rougher than the last. I’m fantasizing about fasting a few days and then taking laxatives to prepare for an enema (4 liters or however much I can handle) followed by silicone lube, and then by inserting a plug—and let the fun stuff begin. So is it safe to leave silicone lube inside me?