My wife is 45 years old and does not have any sex desire. I like sex very much. I love her very much cannot live without her. But she never wants to have sex. My sex life is totally destroyed. For the past 5 years, she is being treated for depression—desvenlafaxine 50 mg at bed time. The medication has made her aggressive and destroyed communication between us. She blames me for everything. I am very upset with her behavior, and sometimes want to kill myself. What should I do?