General information about PE

Althof, S.E. et al. “International Society for Sexual Medicine’s Guidelines for the Diagnosis and Treatment of Premature Ejaculation,” Journal of Sexual Medicine (2010) 7:2947.

Barnes, T. and I. Eardley. “Premature Ejaculation: The Scope of the Problem,” Journal of Sex and Marital Therapy (2007) 33:151.

Chung, E. et al. “Premature Ejaculation: A Clinical Review for the General Physician,” Australian Family Practice (2015) 44:737.

Rowland, D. et al. “Self-Reported Premature Ejaculation and Aspects of Sexual Functioning and Satisfaction,” Journal of Sexual Medicine (2004) 1:225.

Rowland, D. et al. “Attribution Patterns in Men Who Ejaculate Before They Desire: An Internet Survey,” Journal of Sex and Marital Therapy (2016) 42:462.

Tang, W.S. and E.M. Khoo. “Prevalence and Correlates of Premature Ejaculation in a Primary Care Setting: A Preliminary Cross-Section Study,” Journal of Sexual Medicine (2011) 8:2071.

Studies showing that self-help resources help most men cure PE

Kempeneers, P et al. “Clinical Outcomes of a New Self-Help Booklet for Premature Ejaculation,” Journal of Sexual Medicine (2012) 9:2417.

Van Diest, SL et al. “Sex Therapy Through the Internet for Men with Sexual Dysfunction: A Pilot Study,” Journal of Sex and Marital Therapy (2007) 33:115.

Across the lifespan, PE is men’s leading sex problem

Aschka, C. et al. “Sexual Problems of Male Patients in Family Practice,” Journal of Family Practice (2001) 50:773.

Dunn, K.M. et al. “Systematic Review of Sexual Problems: Epidemiology and Methodology,” Journal of Sex and Marital Therapy (2002) 28:399.

Kempeneers, P et al. “Functional and Psychological Characteristics of Belgian Men with Premature Ejaculation and Their Partners,” Archives of Sexual Behavior (2013) 42:51.

Laumann, EO et al. “Sexual Dysfunction Among Older Adults: Prevalence and Risk Factors from a Nationally Representative U.S. Probability Sample of Men and Women 57-85 Years of Age,” Journal of Sexual Medicine (2008) 5:2300.

Laumann, EO et al. “Sexual Dysfunction in the United States: Prevalence and Predictors,” Journal of the American Medical Association (1999) 281:537.

McMahon, C.G. et al. “The Pathophysiology of Acquired Premature Ejaculation,” Translational Andrology and Urology (2016) 5:434.

Rowland, D.L. and C.J. Neal “Understanding Men’s Attributions of Why They Ejaculate Before Desired: An Internet Study,” Journal of Sexual Medicine (2014) 11:2554.

The Kamasutra on PE

Vatsyayana. Translated by W. Doniger and S. Kakar. Kamasutra. Oxford University Press, N, 2003.

Anxiety and PE

www.adaa.org

Risk factors for PE

Ahmed, A.F. et al. “Impact of Varicocelectomy on Premature Ejaculation in Varicocele Patients,” Andrologia (2015) 47:276.

Asadpour, A.A. et al. “The Effects of Varicocelectomy on Patients with Premature Ejaculation,” Nephro-Urology Monthly (2014) 6:e15991.

Brody, S. and P. Weiss. “Erectile Dysfunction and Premature Ejaculation: Interrelationships and Psychosexual Factors,” Journal of Sexual Medicine (2015) 12:398.

Corona, G. et al. “Interplay Between Premature Ejaculation and Erectile Dysfunction: A Systematic Review and Meta-Analysis. Journal of Sexual Medicine (2015) 12:2291.

Kempeneers, P. et al. “Sexual Cognitions, Trait Anxiety, Sexual Anxiety, and Distress in Men with Different Subtypes of Premature Ejaculation and in Their Partners,” Journal of Sex and Marital Therapy (2018) 44:319.

Kempeneers, P et al. “Functional and Psychological Characteristics of Belgian Men with Premature Ejaculation and Their Partners,” Archives of Sexual Behavior (2013) 42:51.

Rajkumar, R.P. and A.K. Kumaran. “The Association of Anxiety with the Subtypes of Premature Ejaculation: A Chart Review,” Primary Care and Companion CNS Disorders (2014) 16:4.

Symonds, T. et al. “How Does Premature Ejaculation Impact a Man’s Life?” Journal of Sex and Marital Therapy (2003) 29:361.

Ventus, D. et al. “No Evidence for Long-Term Causal Associations Between Symptoms of Premature Ejaculation and Symptoms of Anxiety, Depression, and Sexual Distress in a Large Population-Based Longitudinal Sample,” Journal of Sex Research (2017) 54: 264.

Ventus, D. and Jern, P. “Lifestyle Factors and Premature Ejaculation: Are Physical Exercise, Alcohol Consumption, and Body Mass Index Associated with Premature Ejaculation and Comorbid Erectile Problems?” Journal of Sexual Medicine (2016) 13:1482.

How women feel about PE

Burri, A. et al. “Female Partner’s Perception of Premature Ejaculation and It’s Impact on Relationship Breakups, Relationship Quality, and Sexual Satisfaction,” Journal of Sexual Medicine (2014) 11:2243.

Byers, E.S. and G. Grenier. “Premature or Rapid Ejaculation: Heterosexual Couples’ Perceptions of Men’s Ejaculatory Behavior,” Archives of Sexual Behavior (2003) 32:261.

Graziottin, A. and S. Althof. “What Does Premature Ejaculation Mean to the Man, the Woman, and the Couple?” Journal of Sexual Medicine (2011) 8(Suppl. 4):304.

Kaya, C. et al. “Is Sexual Function in Female Partners of Men with Premature Ejaculation Compromised?” Journal of Sex and Marital Therapy (2015) 41:379.

Kempeneers, P et al. “Functional and Psychological Characteristics of Belgian Men with Premature Ejaculation and Their Partners,” Archives of Sexual Behavior (2013) 42:51.

Limoncin, E. et al. “Premature Ejaculation Results in Female Sexual Distress: Standardization and Validation of a New Diagnostic Tool for Sexual Distress,” Journal of Urology (2012) epub ahead of print.

Maseroli, E. et al. “Which Are the Male Factors Associated with Female Sexual Dysfunction?” Andrology (2016) 4:911.

Rowland, D.L. et al. “Premature Ejaculation: Impact on the Female Partner,” Presented at the World Congress of Sexology, 2005.

The sex therapy program for learning ejaculatory control

Althof, S.E. “Psychosexual Therapy for Premature Ejaculation,” Translational Andrology and Urology (2016) 5:475.

Althof, S.E. et al. “International Society for Sexual Medicine’s Guidelines for the Diagnosis and Treatment of Premature Ejaculation,” Journal of Sexual Medicine (2010) 7:2947.

Barnes, T. and I. Eardley. “Premature Ejaculation: The Scope of the Problem,” Journal of Sex and Marital Therapy (2007) 33:151.

Birch. R.W. A Short Book About Lasting Longer. PEC Publishing, 2007.

Chen, C.Q. et al. “Effect of Interventions for Premature Ejaculation in the Treatment of Chronic Prostatitis with Secondary Premature Ejaculation,” Zhongguo Yi Xue Ke (2016) 38:393.

Chen, G.H. et al. “A Clinical Study on Psycho-Behavioral Therapy for Premature Ejaculation,” Zonghua Nan Ke Xua (Chinese journal) (2009) 15:929.

Cooper, K. et al. “Behavioral Therapies for Management of Premature Ejaculation: A Systematic Review,” Sexual Medicine (2015) 3:174.

DeCarufel, F. and G. Trudel. “Effects of a New Functional Sexological Treatment for Premature Ejaculation,” Journal of Sex and Marital Therapy (2006) 32:97.

Grenier, G. and E.S. Byers, “Operationalizing Premature or Rapid Ejaculation,” Journal of Sex Research (2001) 38:369.

Heiman, J.R.. “Sexual Dysfunction: Overview of Prevalence, Etiological Factors, and Treatments,” Journal of Sex Research (2002) 39:73.

Jern, P. “Evaluation of a Behavioral Treatment Intervention for Premature Ejaculation Using a Hand-Held Stimulating Device,” Journal of Sex and Marital Therapy (2014) 40:358.

Kaplan, H.S. PE: How to Overcome Premature Ejaculation. Brunner/Mazel, NY, 1989.

Kaplan, H.S. The New Sex Therapy. Brunner Mazel/New York Times, 1974.

Kilinc, M.F. et al. “Impact of Physical Activity on Patient Self-Reported Outcomes of Lifelong Premature Ejaculation Patients: Results of a Prospective, Randomize, Sham-Controlled Trial,” Andrologia (2017) epub ahead of print.

Kuritzky, L. et al. “Premature Ejaculation: Management in Primary Care,” Patient Care, 1-2005, p. 49.

LaPera, G. and A. Nicastro. “A New Treatment for Premature Ejaculation: The Rehabilitation of the Pelvic Floor,” Journal of Sex and Marital Therapy (1996) 22:22.

Li, P. et al. “Interventional Effect of Behavior Psychotherapy on Patients with Premature Ejaculation,” Zhonghua Nan Ke Xue (Chinese journal) (2006) 12:717.

Lujan, S. et al. “Are Urology Residents Ready to Treat Premature Ejaculation After Their Training?” Journal of Sexual Medicine (2012) 9:404.

Masters, W. and V. Johnson. Human Sexual Inadequacy. Little Brown & Co. 1970.

Mathers, M.J. et al. “Premature Ejaculation in Urological Routine Practice,” Aktuelle Urology (German journal) (2013) 44:33.

Majzoub, A. et al. “Premature Ejaculation in Type 2 Diabetes Mellitus Patients: Association with Glycemic Control,” Translational Andrology and Urology (2016) 5:248.

McCabe, MP. “Evaluation of a Cognitive Behavior Therapy Program for People with Sexual Dysfunction,” Journal of Sex and Marital Therapy (2001) 27:259.

Metz, M. and B. McCarthy. Coping With Premature Ejaculation. New Harbinger Publications, 2003.

Metz, M.E. and J.L. Pryor. “Premature Ejaculation: A Psychophysiological Approach for Assessment and Management,” Journal of Sex and Marital Therapy (2000) 26:293.

Pastore, A.L. et al. “Pelvic Floor Muscle Rehabilitation for Patients with Lifelong Premature Ejaculation: A Novel Therapeutic Approach,” Therapeutic Advances in Urology (2014) 6:83.

Payne, R.E. and R. Sadovsky. “Identifying and Treating Premature Ejaculation: Importance of the Sexual History,” Cleveland Clinic Journal of Medicine (2007) 74:S47.

Porst, H. et al. “The Premature Ejaculation Prevalence and Attitudes (PEPA) Survey: Prevalence, Comorbidities, and Professional Help-Seeking,” European Urology (2007) 51:816.

Rowland, D.L. et al. “Practical Tips for Sex Counseling and Psychotherapy in Premature Ejaculation,” Journal of Sexual Medicine (2011) 8(Suppl 4):342-52.

Rowland, D.L. et al. “The Psychosocial Impact of Premature Ejaculation on Men,” Presented at the World Congress of Sexology, 2005.

Rowland, D. et al. “Self-Reported Premature Ejaculation and Aspects of Sexual Functioning and Satisfaction,” Journal of Sexual Medicine (2004) 1:225.

Sarwer, DB and JA Durlak. “A Field Trial of the Effectiveness of Behavioral Treatment for Sexual Dysfunctions,” Journal of Sex and Marital Therapy (1997) 23:87.

Seagraves, R.T. “Rapid Ejaculation: A Review of Nosology, Prevalence, and Treatment,” International Journal of Impotence Research (2006) 18(Suppl 1):S24.

Serefoglu E.C. and T.R. Saitz. “New Insights on Premature Ejaculation: A Review of Definition, Classification Prevalence, and Treatment,” Asian Journal of Andrology (2012) 14:822.

Shindel, A. et al. “Urologist Practice Patterns in the Management of Premature Ejaculation: A Nationwide Survey,” Journal of Sexual Medicine (2008) 5:199.

Silverberg, S. Lasting Longer: The Treatment Program for Premature Ejaculation. Physicians Medical Press, 1978, 2010.

Simons, J.S. and M.P. Carey. “Prevalence of Sexual Dysfunctions: Results from a Decade of Research,” Archives of Sexual Behavior (2001) 30:177.

Strassberg, D.S. et al. “The Role of Anxiety in Premature Ejaculation: A Psychophysiolgical Model,” Archives of Sexual Behavior (1990) 19:251.

Symonds, T. et al. “How Does Premature Ejaculation Impact a Man’s Life?” Journal of Sex and Marital Therapy (2003) 29: 361.

Tang, W.S. and E.M. Khoo. “Prevalence and Correlates of Premature Ejaculation in a Primary Care Setting: A Preliminary Cross-Sectional Study,” Journal of Sexual Medicine (2011) 8:2071.

Ventus, D. and P. Jern. “Lifestyle Factors and Premature Ejaculation: Are Physical Exercise, Alcohol Consumption, and Body Mass Index Associated with Premature Ejaculation and Comorbid Erectile Problems?” Journal of Sexual Medicine (2016) 13:1482.

Waldinger, M.D. et al. “Proposal for a Definition of Lifelong Premature Ejaculation Based on Epidemiological Stopwatch Data,” Journal of Sexual Medicine (2005) 2:498.

Waldinger M.D. et al. “A Multinational Population Survey of Intra-Vaginal Ejaculation Latency Time,” Journal of Sexual Medicine (2005). 2: 492.

Xia, Y. et al. “Relationship Between Premature Ejaculation and Depression: A PRISMA-Complaint Systematic Review and Meta-Analysis,” Medicine (Baltimore) (2016) 95:e4620.

Antidepressants to treat PE

Castiglione, F. et al. “Current Pharmacological Management of Premature Ejaculation: A Systematic Review and Meta-Analysis,” European Urology (2016) 69:904.

Cormio, L. et al. “The Combination of Dapoxitine and Behavioral Treatment Provides Better Results than Dapoxitine Alone in the Management of Pati9ents with Lifelong Premature Ejaculation,” Journal of Sexual Medicine (2015) 12:1609.

Koyuncu, H. et al. “Deleterious Effects of Selective Serotonin Reuptake Inhibitor Treatment on Semen Parameters in Patients with Lifelong Premature Ejaculation,” International Journal of Impotence Research (2012) 24:171.

McMahon, C.G. et al. “Efficacy and Safety of Dapoxetine for the Treatment of Premature Ejaculation: Integrated Analysis of Results from Five Phase 3 Trials,” Journal of Sexual Medicine (2011) 8:524.

McMahon, C.G. and H. Porst. “Oral Agents for the Treatment of Premature Ejaculation: Review of Efficacy and Safety in the Context of Recent International Society for Sexual Medicine Criteria for Lifelong Premature Ejaculation,” Journal of Sexual Medicine (2011) 8:2707.

McMahon, C.G. and K. Trouma. “Treatment of Premature Ejaculation with Paroxetine (Paxil) as Needed: Two Single-Blind, Placebo-Controlled Crossover Studies,” Journal of Urology (1999) 161:1826.

Mercado, M.G. et al. “What’s the Best Drug Treatment for Premature Ejaculation?” Journal of Family Practice (2008) 57:192.

Mantovani, F. “Pharmacological/Dynamic Rehabilitative Behavioral Therapy for Premature Ejaculation: Result of a Pilot Study,” Archives of Italian Urology and Andrology (2017) 89:148.

Park H.J. et al. “Discontinuation of Dapoxetine Treatment With Premature Ejaculation: A 2-Year Prospective Observational Study,” Sexual Medicine (2017) 5:e99.

Pavone, C. et al. “Premature Ejaculation: Pharmacotherapy Vs. Group Psychotherapy Alone or in Combination,” Archives of Italian Urology and Andrology (2017) 89:114.

Porst, H. “An Overview of Pharmacotherapy in Premature Ejaculation,” Journal of Sexual Medicine (2011) 8(Suppl 4):335.

Pryor, J.L. et al. “Efficacy and Tolerability of Dapoxetine in Treatment of Premature Ejaculation: An Integrated Analysis of Two Double-Blind Randomized Controlled Trials,” Lancet (2006) 368:929.

Waldinger M.D., et al. “Premature Ejaculation and Serotonergic Anti-Depressants-Induced Delayed Ejaculation: The Involvement of the Serotenergic System,” Behavioral Brain Research (1998) 92:111.

Yilmaz, U. et al. “Effects of Fluoxetine (Prozac) on Several Neurophysiological Variables in Patients with Premature Ejaculation,” Journal of Urology (1999) 161:107.

Yue, F.G. et al. “Efficacy of Dapoxetine for the Treatment of Premature Ejaculation: A Meta-Analysis of Randomized Clinical Trials on Intravaginal Ejaculatory Latency Time, Patient-Reported Outcomes, and Adverse Events,” Urology (2015) 875:856.

Erection medications to treat PE

Abu El-Hamd, M. and A. Abdelhamed. “Comparison of the Clinical Efficacy and Safety of the On-Demand Use of Paroxetine, Dapoxetine, Sildenafil and Combined Dapoxetine with Sildenafil in Treatment of Patients with Premature Ejaculation: A Randomized Placebo-Controlled Clinical Trail,” Adrologia (20-17) epub ahead of print.

Bai, Y. et al. “Selective Serotonin Reuptake Inhibitors Plus Phosphodiesterase-5 Inhibitors for Premature Ejaculation: A Systematic Review and Meta-Analysis,” Urology (2015) 86:758.

Martyn-St. James, M. et al. “Phosphodiesterase Type 5 Inhibitors for Premature Ejaculation: A Systematic Review and Meta-Analysis,” European Urology Focus (2017) 3:119.

Ozcan, L. et al. “Effects of Tadalafil 5 mg Dosed Once Daily in Men with Premature Ejaculation,” Urology International (2017) 98:210.

Sun, Y. Efficacy of Phosphodiesterase-5 Inhibitor in Men with Premature Ejaculation: A New Systematic Review and Meta-Analysis,” Urology (2015) 86:947.

Verze, P. et al. “Comparison of Treatment Emergent Adverse Events in Men with Premature Ejaculation Treated with Dapoxetine and Alternate Oral Treatments: Results from a Large Multinational Observational Trial,” Journal of Sexual Medicine (2016) 13:194.

Anesthetics to treat PE

Berkovitch, M. et al. “Efficacy of Prilocaine-Lidocaine Cream in the Treatment of Premature Ejaculation,” Journal of Urology (1995) 154:1360.

Mark, K.P. and I. Kerner. “Event-Level Impact of Promescent on Quality of Sexual Experience in Men with Subjective Premature Ejaculation,” International Journal of Impotence Research (2016) 28:216.

Martyn-St. James et al. “Topical Anesthetics for Premature Ejaculation: A Systematic Review and Meta-Analysis,” Sexual Health (2016) 13:114.

Paick, J.S. et al. “Penile Sensitivity in Men with Premature Ejaculation,” International Journal of Impotence Research (1998) 10:247.

Pu, C. et al. “Topical Anesthetic Agents for Premature Ejaculation: A Systematic Review and Met-Analysis,” Urology (2013) 81:799.

Wyllie, M.G. and J.A. Powell. “The Role of Local Anesthetics in Premature Ejaculation,” BJU International (formerly British Journal of Urology) (2012) epub ahead of print.

Other PE treatments

Cai, T. et al. “Rhodiola Rosea, Folic Acid, Zinc, and Biotin (EndEP) Is Able to Improve Ejaculatory Control in Patients Affected by Lifelong Premature Ejaculation: Results from a Phase 1-II Study,” Experimental Therapies in Medicine (201t6) 12:2083.

Cooper, K. et al. “Complementary and Alternative Medicine for Management of Premature Ejaculation: A Systematic Review,” Sexual Medicine (2017) 5:e1.

Sahin, S. et al. “A Prospective Randomized Controlled Study to Compare Acupuncture and Dapoxetine for the Treatment of Premature Ejaculation,” Urology International (2016) 97:104.

Sansalone, S. et al. “A Combination of Tryptophan, Satureja Montana, Tribulus Terrestis, Phyllanthus Emblica Extracts Is Able to Improve Sexual Quality of Life in Patients with Premature Ejaculation,” Archives of Italian Urology and Andrology (2016) 88:171.

Sunay, D. et al. “Acupuncture vs. Paroxetine for the Treatment of Premature Ejaculation: A Randomized, Placebo-Controlled Clinical Trial,” European Urology (2011) 59:765.

PE in women?

Caravalho, S. et al. “Female Premature Ejaculation: Does This Exist?” Sexologies (2011) 20:215.